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A benchmark for prediction of transcriptomic responses to chemical perturbations across cell types

Neural Information Processing Systems

Single-cell transcriptomics has revolutionized our understanding of cellular heterogeneity and drug perturbation effects. To overcome these limitations, several groups have proposed using machine learning methods to directly predict the effect of chemical perturbations either across cell contexts or chemical space. However, advances in this field have been hindered by a lack of well-designed evaluation datasets and benchmarks. To drive innovation in perturbation modeling, the Open Problems Perturbation Prediction (OP3) benchmark introduces a framework for predicting the effects of small molecule perturbations on cell type-specific gene expression. OP3 leverages the Open Problems in Single-cell Analysis benchmarking infrastructure and is enabled by a new single-cell perturbation dataset, encompassing 146 compounds tested on human blood cells. The benchmark includes diverse data representations, evaluation metrics, and winning methods from our "Single-cell perturbation prediction: generalizing experimental interventions to unseen contexts" competition at NeurIPS 2023.


The Gap Between Open and Closed AI Models Might Be Shrinking. Here's Why That Matters

TIME - Tech

Today's best AI models, like OpenAI's ChatGPT and Anthropic's Claude, come with conditions: their creators control the terms on which they are accessed to prevent them being used in harmful ways. This is in contrast with'open' models, which can be downloaded, modified, and used by anyone for almost any purpose. A new report by non-profit research organization Epoch AI found that open models available today are about a year behind the top closed models. "The best open model today is on par with closed models in performance, but with a lag of about one year," says Ben Cottier, lead researcher on the report. Meta's Llama 3.1 405B, an open model released in July, took about 16 months to match the capabilities of the first version of GPT-4.


IoT and machine learning: Walking hand in hand towards smarter future

#artificialintelligence

IoT machine learning has revolutionized the way businesses operate, by transforming vast amounts of data into actionable insights and decision-making tools. The era of technology is constantly evolving, with new advancements appearing almost every day. One such field that has gained immense popularity in recent times is the combination of Internet of Things (IoT) and Machine Learning (ML). This innovative blend of technologies is opening doors to new business opportunities, and is poised to play a major role in shaping the future of our world. In a world that is becoming increasingly data-driven, IoT machine learning provides a new and exciting avenue for businesses to leverage the power of big data, and gain a competitive edge in the market.


5 robotics predictions for 2023

#artificialintelligence

The past few years have seen many organizations implement tech-driven changes at a rapid pace. As society becomes more digital, embracing technology and effectively managing new processes is key to the success of almost every business. With rapid workplace transformation evident across industries, whether that's moving to hybrid working or adopting new technologies, what can we expect from 2023? Here are five predictions for the coming year. In recent years we have witnessed the development of many different types of sophisticated technologies.


Building a Data-Driven Future with Synthetic Data

#artificialintelligence

Synthetic data will take over real-world data in the future. Synthetic data works just like real-world data, but the difference is that it's artificially created and not based on actual events. Businesses can use synthetic data for various purposes, such as filling the gaps in missing training data they can't acquire or that doesn't yet exist. Think of synthetic data the same way you think about simulating events using actual data. Synthetic data sets are used to simulate events, but the data is manufactured instead of using real-world data.


Why investing in human ingenuity will drive innovation

#artificialintelligence

Life and annuity insurers have adopted a host of new technologies in recent years to drive growth. Artificial intelligence, robotics process automation and data analytics – are only a few of the many new technologies that underwriters have at their disposal today. Insurers are putting all the parts into place for underwriters to improve efficiency and drive new growth -- but they aren't quite there yet. Recent Accenture research found that underwriters feel positive about these new tools but are also concerned about their ability to use them. To realize the full value of their tech investments, insurers must invest not only in technology but also in their workforces to ensure they can use these new technologies properly.


Debayan Deb: Providing Artificial Intelligence- Powered Solutions to Drive Innovation

#artificialintelligence

LENS Corporation is focused on providing an AI-powered solution to multiple problems by enabling machines to view and perceive. It provides state-of-the-art artificial intelligent in-house developed solutions while collaborating with multiple AI and ML developers across the world. Some of the ongoing projects of this company are infant fingerprint recognition, contactless fingerprints, and primate face recognition. Debayan Deb is Co-Founder and CEO of LENS Corporation. His fascination for computer vision quickly turned into a passion that was worth pursuing in 2015.


How Big Data and Open Banking Are Combining To Bring a New Era of Fintech-Driven Banking - DZone Big Data

#artificialintelligence

The rise of technology and digital services has led to increasing customer demands for simplicity and speed. Banks and financial services institutions are continuously searching for new ways to retain and attract customers while aiming to respond to heightened consumer demand for personalized services. For this reason, customer-centric offerings continue to dominate the financial technology (FinTech) landscape. Personalization takes advantage of real-time data and cutting-edge technologies to deliver product or service information to customers. In an extremely competitive financial services sector, there is more pressure than ever for FinTech companies to provide customers with a better experience.


Council Post: Why AI Projects Are Failing At Your Company

#artificialintelligence

My company, Alation, partnered with Wakefield Research to survey senior enterprise data leaders about AI. We wanted to understand how prevalent AI projects are, to understand what drives success and to more generally understand trends. Not surprisingly, we found that almost every enterprise is deploying or has plans to deploy AI. Organizations have copious data -- data that continues to grow daily -- and they have a ton of business problems that they could apply that data to. We've all seen the case studies about how AI helps drive innovation in products and services and improves operational efficiencies and customer experience.